Serum makes profits of up to 2,000 percent ¡ª what Poonawalla might consider ¡°super profits¡± ¡ª and Bharat Biotech up to 4,000 percent. In comparison, based on the estimated cost to make one dose, Pfizer¡¯s and Moderna¡¯s profit margins are 650 percent and 500 percent, respectively.